Microfluidic Innovations Technical Article on the AssayMark System Accepted for Publication

Published: April 2013
Source: Microfluidics and Nanofluidics

Abstract
Current lab-on-a-chip (LoC) devices are assay-specific and are custom-built for each single experiment. Performing an experiment requires scientists or engineers to go through the time-consuming process of designing, fabricating, and testing a chip before conducting the actual experiment. This prolonged cycle can take months to complete, increasing effort and cost and reducing productivity. Similarly, minor modifications to an assay protocol re-incur the overheads of the design cycle. In this paper, we develop a multi-purpose, software-programmable Lab-on-a-Chip(SPLoC), where the user simply writes or downloads a program for each experiment. We describe the components necessary to realize the SPLoC, which include a high-level programming language, an abstract instruction set, a runtime and control system, and a microfluidic device. We describe two key features of our high-level language compiler, and describe a novel variable-volume variable-ratio mixer. Finally, we demonstrate our SPLoC on four diverse, real-world assays.

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Microfluidic Innovations AssayMark System used to synchronize bacteria

Published: October 3, 2012
Source: Chemical & Engineering News
By: Erika Gebel

Left to their own devices, bacterial populations contain a mix of young, middle-aged, and old cells. But scientists studying events that occur at different parts of the microbes’ cell cycles learn more about each phase by studying populations all at the same stage. Researchers have now developed a microfluidic device that automatically syncs bacteria to the same stage for on-chip analysis (Anal. Chem., DOI: 10.1021/ac301565g).

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Microfluidic Innovations announces pre-production version of AssayMark System

Published: May 16, 2012
Source: Purdue Research Park
By: Steve Martin

WEST LAFAYETTE, Ind. – Life-science researchers in academic institutions and industry can use a newly developed system to program lab-on-a-chip devices for experiments at a sub-millimeter scale rather than use custom devices.

Microfluidic Innovations LLC has developed and manufactured a system to help researchers perform experiments at a microfluidic scale using its PLoC (Programmable Lab on a Chip) device and its AssayMark controller and software. The firm is based in the Purdue Research Park of West Lafayette.

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